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I live in an industrial loft in east London (England) which is one room with a mezzanine for a bedroom. A problem I've encountered that I don't think has been mentioned is that I've found maximising your open floor space to wall ratio and your window to wall space ratio has the disadvantage that you have very little room for storage. I haven't found a good way to tackle this yet, and so lots of my possessions are sitting around in trunks, which is not very efficient. I'm considering building a set of deep, wide shelves on one wall that go all the way up to the ceiling (double height) and having a sliding library ladder. That would be fun, but I'm not sure how sensible a solution it will prove to be.