Anti-vaxxers circa 1770

From Catherine the Great:

Fear for herself, her son, and the nation prompted the empress to investigate a new, controversial method of inoculation that assured permanent immunity: the injection of matter taken from the smallpox pustules of a patient recovering from a mild case. This medical technique was being used in Britain and the British North American colonies (Thomas Jefferson was inoculated in 1766) but was shunned in continental Europe as being too dangerous.

Catherine’s willingness to be inoculated attracted favorable notice in western Europe. Voltaire compared what she had allowed Dimsdale to do with the ridiculous views and practices of “our argumentative charlatans in our medical schools.” At the time, the prevailing attitude toward the disease was fatalistic: people believed that, sooner or later, everyone must have it, and that some would survive and some would die. Most refused inoculation. Frederick of Prussia wrote to Catherine urging her not to take the risk. She replied that she had always been afraid of smallpox and wished more than anything to escape this fear. In May 1774, almost six years after Catherine was inoculated, smallpox killed the king of France. Louis XV took to bed a barely pubescent girl who was carrying smallpox. He died soon after, ending a reign of fifty-nine years. His successor, nineteen-year-old Louis XVI, was inoculated immediately.

The imposition of medical precautions led to rioting. Many in Moscow’s terror-stricken population came to believe that the physicians and their medicines had brought the plague to the city. They refused to obey orders forbidding them to gather in marketplaces and churches and to kiss supposedly miraculous icons in hope of protection. Instead, they gathered to seek salvation and solace around these icons. A famous icon of the Virgin at Varvarsky Gate became a magnet; day after day, crowds of diseased people swarmed around her feet. She became the deadliest center of contagion in the city.

Attempting to reduce infection by preventing the formation of crowds, and relying on his authority as a priest, he had the Varvarsky Virgin removed from the city gate under cover of night and hidden. He believed that once the people knew that he was the one responsible, they would go home and the plague-ridden site would be eliminated. Instead, his well-meaning attempt provoked a riot. The crowd, rather than dispersing, was enraged. Ambrosius fled to a monastery and took refuge in a cellar, but the mob pursued him, dragged him out, and tore him apart. The riot was put down by troops, who killed a hundred people and arrested three hundred.